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Showing all 42 items for (author: ciazynska & ka)

EMDB-33748:
Spike_GSAS_6P protomer RBD domain bound with R1-32 Fab and ACE2 with 3:3:3 ratio
Method: single particle / : Liu B, Gao X, Li Z, Chen X, He J, Chen L, Xiong X

EMDB-33760:
Spike_GSAS_6P and R1-32 Fab with 3to1 ratio
Method: single particle / : Liu B, Gao X, Li Z, Chen X, He J, Chen L, Xiong X

EMDB-33764:
SARS-COV-2 Spike_GSAS_6P bound with two R1-32 Fabs
Method: single particle / : Liu B, Gao X, Li Z, Chen X, He J, Chen L, Xiong X

EMDB-33766:
SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs
Method: single particle / : Liu B, Gao X, Li Z, Chen X, He J, Chen L, Xiong X

EMDB-33772:
SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2
Method: single particle / : Liu B, Gao X, Li Z, Chen X, He J, Chen L, Xiong X

PDB-7ydi:
SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region
Method: single particle / : Liu B, Gao X, Li Z, Chen X, He J, Chen L, Xiong X

PDB-7ydy:
SARS-CoV-2 Spike (6P) in complex with 1 R1-32 Fab
Method: single particle / : Liu B, Gao X, Li Z, Chen X, He J, Chen L, Xiong X

PDB-7ye5:
SARS-CoV-2 Spike (6P) in complex with 2 R1-32 Fabs
Method: single particle / : Liu B, Gao X, Li Z, Chen X, He J, Chen L, Xiong X

PDB-7ye9:
SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs
Method: single particle / : Liu B, Gao X, Li Z, Chen X, He J, Chen L, Xiong X

PDB-7yeg:
SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2
Method: single particle / : Liu B, Gao X, Li Z, Chen X, He J, Chen L, Xiong X

EMDB-33453:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-1 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33454:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-211 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33455:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-122 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33456:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33457:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33458:
Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33459:
Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33460:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), incubated in Low pH after 40-Day Storage in PBS, Locked-2 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33461:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site) after 40-Day Storage in PBS, Closed Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33462:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), incubated in Low pH after 40-Day Storage in PBS, Closed Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33463:
Structure of SARS-CoV-2 D614G spike protein (single Arg S1/S2 cleavage site), Closed Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

EMDB-33464:
Structure of SARS-Cov-2 D614G spike protein (single Arg S1/S2 cleavage site), Open Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Carter AP, Xiong X, Briggs JAG

PDB-7xtz:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-1 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Zhang X, Carter AP, Xiong X, Briggs JAG

PDB-7xu0:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-211 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Zhang X, Carter AP, Xiong X, Briggs JAG

PDB-7xu1:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-122 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Zhang X, Carter AP, Xiong X, Briggs JAG

PDB-7xu2:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Zhang X, Carter AP, Xiong X, Briggs JAG

PDB-7xu3:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Zhang X, Carter AP, Xiong X, Briggs JAG

PDB-7xu4:
Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Zhang X, Carter AP, Xiong X, Briggs JAG

PDB-7xu5:
Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Zhang X, Carter AP, Xiong X, Briggs JAG

PDB-7xu6:
Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), incubated in Low pH after 40-Day Storage in PBS, Locked-2 Conformation
Method: single particle / : Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Zhang X, Carter AP, Xiong X, Briggs JAG

EMDB-11329:
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x2 disulphide-bond mutant, G413C, V987C, single Arg S1/S2 cleavage site)
Method: single particle / : Qu K, Xiong X, Scheres SHW, Briggs JAG

EMDB-11330:
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
Method: single particle / : Qu K, Xiong X, Scheres SHW, Briggs JAG

EMDB-11331:
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Locked State
Method: single particle / : Qu K, Xiong X, Scheres SHW, Briggs JAG

EMDB-11332:
Structure of SARS-CoV-2 Spike Protein Trimer (single Arg S1/S2 cleavage site) in Closed State
Method: single particle / : Qu K, Xiong X, Scheres SHW, Briggs JAG

EMDB-11333:
Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
Method: single particle / : Qu K, Xiong X, Scheres SHW, Briggs JAG

EMDB-11334:
Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Locked State
Method: single particle / : Qu K, Xiong X, Scheres SHW, Briggs JAG

PDB-6zox:
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x2 disulphide-bond mutant, G413C, V987C, single Arg S1/S2 cleavage site)
Method: single particle / : Xiong X, Qu K, Scheres SHW, Briggs JAG

PDB-6zoy:
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
Method: single particle / : Xiong X, Qu K, Scheres SHW, Briggs JAG

PDB-6zoz:
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Locked State
Method: single particle / : Xiong X, Qu K, Scheres SHW, Briggs JAG

PDB-6zp0:
Structure of SARS-CoV-2 Spike Protein Trimer (single Arg S1/S2 cleavage site) in Closed State
Method: single particle / : Xiong X, Qu K, Scheres SHW, Briggs JAG

PDB-6zp1:
Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
Method: single particle / : Xiong X, Qu K, Scheres SHW, Briggs JAG

PDB-6zp2:
Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Locked State
Method: single particle / : Xiong X, Qu K, Scheres SHW, Briggs JAG

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

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External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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